I'm not very knowledgeable about the pros and cons of various pickup specs, but I really like the idea of having two "unmatched" pickups, and being able to switch between neck and bridge for very different purposes.

This is mostly stimulated by Joe Duplantier's setup (https://www.charvel.com/gear/shape/s...any/2976181357) , with DiMarzio PAF 36th Anniversary in the neck, and a DiMarzio Fortitude in the bridge (based on the PAF), with a switch and volume pot only.

I'm wondering if something like a Tonerider Alnico 2 Classics in the neck paired with a Tonerider Octane Alnico 8 in the bridge would work.
https://www.pitbullguitars.com/shop/...kel-humbucker/
https://www.pitbullguitars.com/shop/...mbucker-black/

Purely personal choice? Or, yeah nah?