Not if I want to stay married. The AC connects with the rest of the house, so it would spread whatever goes into the air to the rest of the house. To keep things cool, the garage "vents" mostly to the rest of the house rather than to outside. Also it functions as my office (I work from home several days a week). I only apply the top coats, shellac, and some no-VOC water-based hardners or grain fillers in the garage. My wife is also an environmental engineer, so there are many ways I can get into trouble. It's also why I use MTN94 pretty much exclusively for color. It does not seem bothered by heat and humidity and is very low VOC, so I can spray outside even in Miami weather, and it can cure indoors.