Simon, thank you very much for the helpful answer!
It's funny what you'll discover when you forget to test fit new hardware. Turns out the pickups are just wider than the originals, and the spacing on the saddles is a little narrower than the original bridge, so the strings didn't fit well if the pickups were horizontal. Once I turned them diagonally they lined up much better with the strings. The single coil poles are centered, and the humbucker poles are evenly distributed on either side of the string. Based on what Simon mentioned, I'm interested to hear how it sounds with this change.
Routing this time was much more nerve wracking, and next time I'll make/buy templates as free handing was a little rough going. There are a few mistakes, but nothing I can't fix with a little veneer, glue, and sawdust. I'm pretty happy overall though, and now it just needs some sanding and tidying up. After that it's time to sand the body, fill left over holes and start painting!
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