If any of you guys are using your Audio Interfaces with a PC, there's a handy little App for PCs that can help you get the best performance out of your Audio Interface, it's called DPC Latency Checker, what does DPC mean?, DPC is short for Deferred Procedure Call, basically a DPC is a signal that the CPU gets while it's working on something, when the CPU gets a DPC it stops what it's working on and starts working on whatever it is that generated the DPC, usually a peripheral, such as the LAN, or Bluetooth for example, the time taken for the CPU to stop what it is currently doing when it gets a DPC to when it starts working on whatever generated the DPC, is what's called the DPC Latency, when it comes to Audio recording and playback, having a system with low DPC Latency is critical for good performance without Audio breakup or noticeable dropouts, here's a link to the website where you can download the App, I don't know what the Mac equivalent is, or if there is even one though, it's a free download:
http://www.thesycon.de/deu/latency_check.shtml