Not keen on the synthetic nuts. The ones with graphite in always seem dirty looking as the graphite comes out and spreads over the surface.
The downside of brass is that it's a lot softer than steel, so over time the strings will cut deeper slots into the nut, which if you've already taken the slots to their lowest level possible before buzzing for the lowest action, does reduce the lifetime of the nut. Gibson found this out very quickly with their 2015 all-in-one zero-fret nut arrangement, which started out as brass but had to be swapped to titanium fairly quickly. Less important for saddles, where you can simply raise the saddles up to compensate for wear.
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