Well, I finally managed to buy myself a full legal copy of Reason 10 earlier this week, it installed on my studio PC with relatively few issues although I did have to go through the process of downloading about 6Gb worth of extra content before I could try playing one of the demo songs, the good news is I only had to do that once, the registration process was relatively painless too, the software registration is linked to your account at the Proppellerhead website, anyway, the software sounds really good and it seemed to work with my Focusrite saffire Pro 40 audio interface with no issues, it should work fine with all audio interfaces that support the ASIO protocol (for PCs, I'm not sure what the current intel Macs are using), seems to be running fine on Windows 10 64 bit.