
Originally Posted by
Simon Barden
Two different power sources is far worse scenario for creating ground loops than a single power source. It's always best to run connected equipment from the same power outlet using multi-way distribution boards (unless the equipment uses balanced signal cables and has shield ground lift switches available).
But you're unlikely to run into any serious noise issues until you start using digital FX pedals, which is where the multiple ground paths can really make a difference. Using a PSU with isolated power supplies certainly helps here, but even then, using two amps, you may then need to use a switcher with isolated outputs.