
Originally Posted by
Simon Barden
Not quite the only difference. It's only a small one but the tuning key normally sits on the side of the post away from the player. If you rotate the tuners from a R/H set, then the keys will be nearer the player. It will still work, but it might look a little strange as you get used to guitars looking a certain way.
The other thing to consider is that often the screw fixing lug (if there is one) sticks in towards the middle of the headstock at a 45° angle to the line of the tuners. If you get tuners like this and don't get a L/H set, then those lugs will be facing the outside of the headstock and be very near the edge. If you then knock a tuner peg, the rotational force force might be strong enough to split the wood open.
I think you're safer if you get a L/H set.