Yeah a lot of Daws especially Pro Tools hates Via chipsets. So you've reinstalled the Saffire Pro then restarted sometimes if You don't restart it doesn't discover the latest drivers. Try to do a rescan in devices if it's showing in the devices list. Also try another cable. My a Eleven rack played up recently it was a cable that had decided to go walkabout. Have you checked to see if you have the latest firmware Doc.